Replacement Kit Procedures, October 2008 To Whom It May Concern: According to our records, batch 001 of Totect® emergency treatment kits are set to expire on November 30, 2008. By purchasing a Totect® emergency treatment kit at $14,750, you are entitled to a six-year replacement kit policy. In accordance with our six-year replacement kit policy, you are entitled to a new Totect® emergency treatment kit. To claim your Totect® replacement kit, please follow the instructions below: 1. On or after November 1, 2008, please contact your authorized distributor (ASD or Oncology Supply) and request a Return Goods Authorization (RGA). 2. Upon your request, your authorized distributor will ship out a RGA along with a new Totect® kit. This process ensures that your facility is never unprotected should you experience an anthracycline extravasation. 3. Securely package your soon-to-expire or expired Totect® emergency treatment kit. Affix the RGA to the package and ship back to your distributor. 4. Your facility may be billed by your distributor for a new kit, however your distributor will credit your account when the soon-to-expire or expired kit is returned. Once you receive the new kit and the RGA, you should return the soon-to-expire or expired kit back to your distributor within 15 days. Please review the Totect® Six-Year Replacement Kit Policy at www.totect.com/replacementpolicy and adhere to points 1 - 7 prior to returning your kit. On behalf of TopoTarget, I would like to thank you for your support and your continuing commitment to provide exceptional patient care. | 
