| | COMMITMENT to EXTRAVASATION TREATMENT |

| Novel research led to the only FDA approved product for treating anthracycline extravasation. |

| TOTECT® may reduce the providers medico-legal risks and healthcare costs associated with anthracycline extravasations. |

| TopoTarget provides the educational platform to increase awareness, detection and prevention of anthracycline extravasations. |

| TOTECT® has orphan drug marketing exclusivity treating anthracycline extravasations. |
|
|